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Matrix Metalloproteinase_9 and Myeloperoxidase Expression. Quantitative Analysis by Antigen.pdf

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Matrix Metalloproteinase_9 and Myeloperoxidase Expression. Quantitative Analysis by Antigen

Carolina M. Maier, Lily Hsieh, Fengshan Yu, Paige Bracci and Pak H. Chan Antigen Immunohistochemistry in a Model of Transient Focal Cerebral Ischemia Matrix Metalloproteinase-9 and Myeloperoxidase Expression : Quantitative Analysis by Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright ? 2004 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231Stroke doi: 10.1161/01.STR.0000125861.55804.f2 2004;35:1169-1174; originally published online April 1, 2004;Stroke. /content/35/5/1169 World Wide Web at: The online version of this article, along with updated information and services, is located on the //subscriptions/ is online at: Stroke Information about subscribing to Subscriptions: /reprints Information about reprints can be found online at: Reprints: document. Permissions and Rights Question and Answer process is available in the Request Permissions in the middle column of the Web page under Services. Further information about this Once the online version of the published article for which permission is being requested is located, click can be obtained via RightsLink, a service of the Copyright Clearance Center, not the Editorial Office.Strokein Requests for permissions to reproduce figures, tables, or portions of articles originally publishedPermissions: by guest on July 24, 2012/Downloaded from Matrix Metalloproteinase-9 and Myeloperoxidase Expression Quantitative Analysis by Antigen Immunohistochemistry in a Model of Transient Focal Cerebral Ischemia Carolina M. Maier, PhD; Lily Hsieh, BA; Fengshan Yu, MD; Paige Bracci, PhD; Pak H. Chan, PhD Background and Purpose—Expression of matrix metalloproteinases (MMPs), proteolytic enzymes that degrade extracel- lular proteins, is altered after ischemia/reperfusion injury and may contribute to blood–brain barrier (BBB) breakdown. Neutrophils, a source of reactive oxygen species and MMP-9, infiltrate damaged tiss