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Lowerandmiddleureter URS_Vibrolith P224
222
labyrinth and vestibule via round window1. In our
series right and left middle ear pressure values
were significantly different in cases with nausea
and vomiting that’s why we concluded that
difference in middle ear pressures of right and left
ear causes nausea and vomiting.
As a result, N2O use seems to be inappropriate for
brief operations because it inceases MEP.
However, in long term operations N2O used with
remifentanil has no effect on MEP as well as on
nausea and vomiting. Difference between right
and left MEP values is an important factor
increasing nausea and vomiting frequency and this
should be further supported by future studies with
larger sample size.
REFERENCES
1. Simpson G, Reedy RL. Middle ear pressure changes after nitrous
oxide anesthesia and its effect on postoperative nausea and vomiting.
Laryngoscope 2004;114: 883-6.
2. Perreault L, Normandin N, Plamondon L. Tympanic membrane
rupture after anesthesia with nitrous oxide. Anesthesiology 1982;57: 325-6.
3. White PF. Spontaneous rupture of tympanic membrane occurring
in the absence of middle ear disease. Anesthesiology 1983;59: 368-9.
4. Golembiewski J, Chernin E, Chopra T. Prevention and treatment of
postoperative nausea and vomiting. American Journal of Health-System
Pharmacy 2005; 62: 1247-61.
5. Palazzo MGA, Strunin L. Anaesthesia and emesis. I: Etiology. Can
Anaesth Soc J 1984; 31: 178-87.
6. Armstrong HG, Heim JW. The effect of flight on the middle ear.
JAMA 1937;109: 417-21.
7. Koivunen P, Alho OP, Uhari, M, Partanen, A, Luotonen, J. General
anesthesia with and without nitrous oxide (N2O) and the weight of middle
ear effusion in children undergoing adenoidectomy and tympanostomy.
Laryngoscope 1996; 106: 724-6.
8. Kubota T, Kazuyoshi H, Noriaki O, Tadanobu Y, Akimasa M, Asahai
M, et al. Middle-ear pressure variations during total intravenous anesthesia
with propofol, fentanyl, and ketamine. J Anesth 1998;12: 17-20.
9. Thomsen KA, Terkilds
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