创伤性脑损伤后损伤扣带和脑干胆碱核群间出现神经旁路是慢性期患者短期记忆恢复的机制.docxVIP

SICENCE新闻发布 作者：Han Do Lee 稿号：NRR-D-14-00342 创伤性脑损伤后损伤扣带与脑干胆碱核群间出现神经旁路:是慢性期患者短期记忆恢复的机制？ 来自韩国岭南大学医学院的Sung Ho Jang博士等应用弥散张量纤维束成像评估创伤性脑损伤后慢性期伴短期记忆恢复的1例患者损伤扣带与脑干胆碱核群间的神经旁路。该报道纳入1例13岁男性患者，脑创伤后2个月无意识和4个月的创伤后记忆缺失，伤后5个月弥散张量纤维束成像显示，脑创伤患者损伤扣带回和脑干胆碱核群间未发现有神经旁路。患者的短期记忆障碍在伤后12个月恢复至正常水平，此时的弥散张量纤维束成像评估显示，患者右侧损伤扣带和右脑干胆碱核群间存在神经旁路。 扣带的功能涉及记忆的形成， 其提供起始于内侧隔核、斜角带垂直部和Meynert基底核至大脑皮质的胆碱能神经支配。弥散张量纤维束成像能够使扣带三维可视化。虽然弥散张量成像已用于损伤扣带恢复机制，即损伤扣带与脑干胆碱核群神经旁路的研究，但研究仍不充分。Sung Ho Jang博士等采用伤后弥散张量纤维束成像随访的手段，发现损伤扣带与脑干胆碱核群间出现神经旁路。该结果将为开发治疗损伤扣带的新手段提供基础。文章发表于《中国神经再生研究（英文版）》杂志2015年3期。 Article: Appearance of a neural bypass between injured cingulum and brainstem cholinergic nuclei of a patient with traumatic brain injury on follow-up diffusion tensor tractography images by Han Do Lee, Sung Ho Jang (Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, 317-1, Daemyung dong, Namku, Daegu, Republic of Korea) Lee HD, Jang SH (2015) Appearance of a neural bypass between injured cingulum and brainstem cholinergic nuclei of a patient with traumatic brain injury on follow-up diffusion tensor tractography images. Neural Regen Res 10(3):498-500. 欲获更多资讯：  HYPERLINK / Neural Regen Res The mechanism underlying short-term memory recovery from chronic traumatic brain injury Dr. Sung Ho Jang, College of Medicine, Yeungnam University, Republic of Korea and his colleagues found a neural bypass between injured cingulum and brainstem cholinergic nuclei of a 13-year-old male patient with traumatic brain injury on follow-up diffusion tensor tractography images. The patient lost consciousness for 2 months and experienced post-traumatic amnesia for 4 months from the time of the accident. A neural bypass between injured cingulum and brainstem cholinergic nuclei was not observed on 5-month diffusion tensor tractography images. The patient’s short term memory disorder was recovered to normal level at 12 months. A