达立通颗粒治疗功能性消化不良的成本-效果分析.pdfVIP

药物与临床 Drugs and Clinic 达立通颗粒治疗功能性消化不良的成本-效果分析 范长生1，何敏媚2 1. 北京医药卫生经济研究会，北京 100052；2. 北京中医药大学管理学院，北京 100029 [摘要] 目的：通过对达立通颗粒现有文献的梳理，全面掌握当前达立通颗粒研究文献现状，在此基础上对达立通颗粒与莫沙 必利治疗功能性消化不良的成本-效果进行分析。方法：采用meta分析方法，系统的评估达立通颗粒治疗功能性消化不良的效 果，采用成本-效果分析方法评价达立通颗粒与莫沙必利治疗功能性消化不良的经济性。结果：达立通颗粒组治疗功能性消化 不良的显效率和总有效率略高于莫沙必利组，达立通颗粒安全性良好，不良事件发生率低于莫沙必利组；在为期4周的治疗期 间，达立通颗粒组与莫沙必利组相比，效果较好，但成本略高。结论：达立通颗粒与莫沙必利相比，治疗功能性消化不???具 有较好的效果优势，影响其增量成本效果比的主要因素是价格。 [关键词] 达立通颗粒；莫沙必利；功能性消化不良；成本-效果分析 [中图分类号] R956　　[文献标识码]　A　　[文章编号]　1672-2809(2015)06-0024-11 Cost-effectiveness Analysis of Dalitong Granule in Treatment of Functional Dyspepsia FAN Chang-sheng1, HE Min-mei2 1. Beijing Medical and Health Economic Research Association, Beijing 100052, China; 2. School of Management, Beijing University of Chinese Medicine,Beijing 100029, China [Abstract] Objective: A comprehensive understanding of the current situation of Dalitong granule research was achievedby literature retrieving.Cost-effectiveness analysiswas performed thereafter on Dalitong granule and mosapride in treating functional dyspepsia. Method: The effectiveness of Dalitong granule in the treatment of functional dyspepsia was evulated with meta analysis. The economic bene?t of Dalitong granule and mosapride in treating functional dyspepsia was evaluated with costeffectiveness analysis. Results: The obvious effective rate and total effective rate of Dalitong granule in the treatment of functional dyspepsia were slightly higher than mosapride.Dalitong grunule had good safety pro?le, and the incidence of adverse events was lower than mosapride. During the 4 weeks of treatment, Dalitong granule had better effects than mosapride, but the cost was slightly higher. Conclusion: Dalitong granule had advantage in treating functional dyspepsia compared to mosapride. The incremental cost effectiveness ratio was mainly in?uenced by the price. [Key words] Dalitong Granule; Mosapride; Functional Dyspepsia; Cost-effectiveness Analysis 能性消化不良(Fu