兔脊髓损伤后钠钾钙镁含量变化及临床意义.PDF

( 18 ( 中国骨伤 1999 年 5 月第 12 卷第 3 期 兔脊髓损伤后钠钾钙镁含量变化及临床意义 申才良 江曙 董英海 张巽 安徽医科大学第一附属医院( 合肥 230022) 摘要 目的 研究脊髓损伤前后血清及 脊髓内 钠、钾、钙、镁 含量的 变化, 为临床 治疗脊 髓损伤 提 供依据。方法 30 只家兔用改良 Allen 氏法造成脊髓损伤, 6 只家兔暴露脊髓不造成损伤。在伤前和伤后 6h、24h、48h、72h 及 6d, 用离子选 择电极法 和原子吸收 光谱法测 定血清和脊 髓组织中离 子钠、钾、钙 、镁 和 总钠、钾、钙、镁含量。结果 脊髓损伤后, 血清中离子钙含量升高, 总镁含量 下降; 脊 髓组织中 总钙、总 钠 含量升高, 总镁、总钾含量下降。结论 脊髓损伤后体内微量元素发生了不同程度的变化。 关键词 脊髓损伤 离子 微量元素 Changes of the Contents of Na, K, Ca and Mg in Rabbits after Spinal Cord Injury and Their Clinical Sig nificance Shen Cailiang, Jiang Shu , Dong Yinghai, et al . The First Aff iliated H ospital of A nhui Medical University (H efei 230022) Abstract Objective To study the changes of the contents of Na, K , Ca and Mg in serum and spinal cord tissue before and after spinal cord injury( SCI) to provide the foundation for clinical treatment. Methods 30 rabbits were ap plied to spinal cord injury with modified Allen! s method, and the spinal cord in 6 rabbits was exposed only. Before SCI or 6h, 24h, 48h, 72h and 6d after SCI, the contents of free and total Na, K, Ca and Mg were measured with ionselective electrodes and atomic absorption spectrometry. Results After SCI, the content of free Ca2+ was increased and total Mg2+ was declined in serum; the contents of total Na+ and Ca2+ were increased, but total K+ and Mg2+ were decreased in spinal cord tissue. Conclusion The contents of trace elements in the body were changed in different extent after SCI. Key words Spinal cord injury Ions Trace elements 脊髓损伤后, 损伤 区离 子失衡 在继 发性 损害 病理 采血,