剖宫产术围手术期抗菌药物使用调查分析.PDF

中国药事 2017 年 1 月 第 31 卷 第 1 期 101 剖宫产术围手术期抗菌药物使用调查分析 邵云,任艳丽,付强,张海礁,郭华（郑州大学第三附属医院，郑州 450052） 摘要 目的：了解医院剖宫产手术抗菌药物使用情况，为促进临床合理使用抗菌药物提供依据。方法： 采用回顾性调查方法对随机抽取的我院 2014 年 7 月 -2014 年 9 月 110 例剖宫产手术患者应用抗菌药物情 况及术后患者体温、炎症指标情况进行统计分析。结果：110 例剖宫产手术患者围手术期全部使用了抗菌 药物，用药频度较高的药品是头孢西丁、五水头孢唑林、头孢唑林、奥硝唑，抗菌药物平均给药时间为 2.27 天，联合用药率为 10%，术后感染率 3.64%。结论：我院剖宫产术围手术期抗菌药物的预防性使用 趋于合理，术后感染率低，但少数病例仍存在药物选择、用药天数、联合用药等方面的欠合理之处。 关键词： 临床用药；案例分析；剖宫产术；抗菌药物；围手术期；合理用药 中图分类号：R969.3 文献标识码：A 文章编号：1002-7777(2017)01-0101-06 doi:10.16153/j.1002-7777.2017.01.020 Investigation and Analysis of Antibiotics Use in Cesarean Operation Shao Yun, Ren Yanli, Fu Qiang, Zhang Haijiao, Guo Hua（The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China） Abstract Objective:? To investigate the use of antibiotics in cesarean operation so as to provide the basis for reasonable application of antibiotics. Methods: The application of antibiotics in cesarean-operation patients was retrospectively and statistically analyzed. The temperature and inflammation marker of postoperative patients were analyzed. Results: Totally 110 cases of cesarean-operation patients used antibiotics. The antibiotics with frequent application included cefoxitin, cefazolin pentahydrate, cefazolin and ornidazole. Antibiotics were used for 2.27 days averagely. The proportion of combined-antibiotics was 10.0%, and the postoperative infection rate was 3.64%. Conclusion: The use of antibiotics in cesarean operation tended to be reasonable, and the rate of postoperative infection was low, but unreasonable drug selection, duration of medication and combined medication were still found in a small number of cases. Keywords: clinical medication; case analysis; cesarean operation; antibiotics; preoperative period; rational use of drugs 自2011年卫生部启动为期3年的抗菌药物专项 者多，导致许多患者需行剖宫产术，抗菌药