转基因动物技术 课夹漫.pptVIP

Transgenic Technology;Definition Transgenic technology refers to the genetic engineering of an organism so that its genomic DNA is altered to over- or underexpress certain genes. ;Transgenic technique Gene Knock Out Gene Knock In Gene Knock Down Gene Trapping mouse, rabbit, rat, sheep, pig, caw etc.;The 2007 Nobel Prize in physiology or medicine is awarded for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells. ;Evans’s work: The ES cells; Mario Capecchi and Oliver Smithies, independently of each other, discovered how homol