46 patients with non-small cell lung cancer tumor markers in patients before and after the monitoring and analysis.docVIP
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46 patients with non-small cell lung cancer tumor markers in patients before and after the monitoring and analysis
PAGE \* MERGEFORMAT 11
46 patients with non-small cell lung cancer tumor markers in patients before and after the monitoring and analysis
[Keywords:] non-small cell lung cancer, tumor markers, dynamic monitoring
TM, especially in non-small cell lung cancer (NSCLC) treatment in the increasingly important role. But so far, TM in lung cancer diagnosis and treatment of lung cancer is still the main screening and diagnosis. This dynamic monitoring of NSCLC patients before surgery and surgical period of time after serum carcinoembryonic antigen (CEA, carbohydrate antigen 125 (CA125, carbohydrate antigen 15 3 (CA15 3 and neuron specific enolase (NSE4 species change TM to investigate the TM in lung cancer surgery the clinical significance.
1 Materials and Methods
1.1 study
Select 4 August 2009 in my 46 cases of surgical treatment in patients with primary lung cancer (case group, surgical resection of lung cancer are (lung, double-leaf or the side of the resection of lung mediastinal lymph node dissection plus bronchial paraneoplastic surgery), after 3 months found no recurrence, lymph node metastasis and distant metastasis. including 28 males and 18 females, aged 44 to 78 years, mean age (55.3 + -6.42 years; after routine pathological distribution was: squamous cell carcinoma in 20 cases, adenocarcinoma 26 cases; TNM staging: b ~ b of the 22 cases, a ~ b of 24 cases. Select the same period in the hospital health examination in 27 cases as control group, of which 17 males 10 females, aged 44 to 72 years, mean age (51.86 + -1.49 years.
1.2 Specimen Collection and Processing
Case group were collected 1 d before surgery and postoperative day 7, after 1,2,3 months of early morning fasting blood 4 ml, and get healthy early morning fasting blood 4 ml. Separation of serum, -20 . electrochemiluminescence detector and associated tumor markers detection kit, Roche kit produced by the United States production. four tumor markers in the reference value as
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