About berberine on type 2 diabetes (damp-type) β-cell function.docVIP

 PAGE \* MERGEFORMAT 14 About berberine on type 2 diabetes (damp-type) β-cell function [Abstract]: Objective berberine on type 2 diabetes (damp-type) β-cell function. Methods of type 2 diabetes were randomly selected damp type of TCM is 60 patients divided into control and experimental group, 30 patients in each group, as a basis for application of metformin treatment, 2 weeks after the test group were treated with berberine, the total 8 weeks. observe the test group before and after the blood glucose, insulin, glycated hemoglobin, C reactive protein and the total score and TCM changes in individual symptom scores, insulin sensitivity index (IAI), insulin resistance index (HOMA-IR), β cell secretion index (HOMA-β) calculated the improvement of pancreatic β cell function. Results Group 2 indicators before and after the test changed significantly (P lt;0.05), the test group of indicators to improve significantly, between the 2 groups were significantly different (P lt;0.05), the experimental group improved β-cell function is most evident. Conclusion Berberine has obvious improve β-cell function, and promote secretion of insulin and reduce insulin resistance and increase the role of insulin sensitivity. [Keywords:] berberine type 2 diabetes mellitus type damp β-cell function Abstract: Objective To observe the effect of berberine to islet β-cell function in type 2 diabetes mellitus (damp-heat type). Methods 60 patients with type 2 diabetes mellitus (damp-heat type) were randomly divided into 2 groups, under basic treatment of 2 weeks with metformin, the treatment group was given berberine. After 8 weeks, the changes in the levels of blood glucose, insulin, HbA1c, CRP and the grade of traditional Chinese medicine individual event symptom and general integral symptom were observed. Apply the formular to evaluate the pancreas’s function. Results Each group had notable difference before and after the experiment in many aspects, especially in treatment group.