Abrus mollis in vitro inhibitory effect on HBsAg and HBeAg.docVIP

 PAGE \* MERGEFORMAT 6 Abrus mollis in vitro inhibitory effect on HBsAg and HBeAg Author: Chen Xiao Bai Han Yu Jian Xu Jian Pan Wang Xiaoping ZHAO Shi-Hua GAN Yao-kun [Abstract] Objective To observe the Abrus mollis in vitro inhibition of HBsAg and HBeAg. Method to extract and alcohol Abrus mollis such capacity, the titer of 1:64 positive serum HBsAg and HBeAg mixed, so that the concentration of Abrus mollis after mixing, respectively 96,48,24,12 and 6 g / L with phosphate buffer with 1:64 mixed with positive serum HBsAg and HBeAg in cooperation blank control. Each group of 6, 37 ℃ water bath, after 8 h and 16 h, using ELISA, the OD value of HBsAg and HBeAg were observed on the inhibition of HBsAg or HBeAg. Results Abrus mollis alcohol extract of serum HBsAg and HBeAg were inhibited, can reduce the concentration of HBsAg and HBeAg, showing a clear dose-and time-response relationship. Abrus mollis in which the role of 16 h, the concentration of 96,48 g / L when HBsAg, HBeAg most obvious inhibitory effect (P amp;lt;0.05). Conclusion Abrus mollis in vitro with a more visible role in anti-HBsAg and HBeAg. [Keywords:] Abrus mollis hepatitis B surface antigen (HBsAg) Hepatitis E antigen (HBeAg) inhibition Herba Abri Abrus cantoniensis Hance and Abrus mollis Abrus m ollis Hance for Abrus leguminous plants, is commonly used Chinese herbal medicine, is also one of China’s export of herbal species [1]. With Qingrejiedu, dampness, promoting blood circulation, relieve pain and other Shugan efficacy of clinical medicine mostly compound can be used for jaundice, Xie Lei uncomfortable, Weiwanxiashu pain, acute and chronic hepatitis, mastitis embolism, especially in the widely used in the treatment of hepatobiliary disease, and to achieve better results. China’s Guangdong, Guangxi and other places rich in JGC resources, Guangxi Yulin Pharmaceutical Co., Ltd production of bile Liver care medicine ‘JGC capsule’ is to Abrus mollis as the main raw material. In order to better