Acute coronary syndrome patients aged P selectin glycoprotein -a of fibrinogen and high sensitivity C reactive protein and clinical significance.docVIP

 PAGE \* MERGEFORMAT 9 Acute coronary syndrome patients aged P selectin glycoprotein /a of fibrinogen and high sensitivity C reactive protein and clinical significance Study: Hong Chen Qiang Wang Yinqiu Lin Lai Heng Long Li Lu Linxiang of Ge Yu [Abstract] Objective To observe the acute coronary syndrome (ACS) patients with platelet activation P selectin (CD62p), glycoprotein (GP) b / a, fibrinogen (FIB-C) and vascular inflammatory markers in high-sensitivity C reactive protein (hs-CRP) and its clinical significance. Methods 100 patients with ACS in patients with early morning fasting blood pumping elbow determined by flow cytometry in serum CD62p and GP b / a receptor complex expression; compared with the scattering Turbidimetric Determination of the level of plasma FIB-C; by latex immunoassay kit enhanced turbidimetry of serum hs-CRP levels. choose 40 cases of healthy and stable angina pectoris (SAP) 50 patients were compared. Results ACS Unstable angina patients (UAP) group plasma CD62p, GP b / a, FIB-C and the expression of hs-CRP were significantly higher than control group (all P lt;0.01) and SAP group (P lt;0.05) ; acute myocardial infarction (AMI) group was significantly higher than that of UAP group (P lt;0.05). coronary artery disease in varying degrees different from the above-mentioned indicators, acute occlusion group (AMI group) than in UAP group, three lesions group (all P lt; 0.05), three lesions was higher than two-vessel disease group (all P lt;0.05), double vessel disease group than in the single-vessel group was significantly higher (P lt;0.05). ACS with diabetes mellitus or impaired glucose tolerance in patients CD62p, GP b / a, FIB-C and hs-CRP levels were significantly higher than normal blood glucose in the ACS group (P lt;0.05, P lt;0.01), and platelet activation and inflammatory cytokine expression levels were positively correlated. Conclusion Elderly ACS patients CD62P, GP b / a, FiB-C and hs-CRP levels significantly in