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Acute hemolytic anemia in laboratory diagnosis
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Acute hemolytic anemia in laboratory diagnosis
Acute hemolytic anemia due to destruction of red blood cells caused by a large number of ischemia, hypoxia and its metabolites, can be important to organ damage, severe cases can cause coma, shock and acute renal failure, if not save, can be life-threatening . clinically not uncommon, and its rapid onset, the condition dangerous. Therefore, the time to establish the diagnosis of hemolytic anemia, as soon as possible to identify the reasons for active and effective treatment of acute hemolytic anemia is to save the key to success.
1 Clinical classification of hemolytic anemia Clinically, hemolytic anemia can be divided into acute and chronic hemolysis hemolysis. Abrupt onset of acute hemolysis, can be sudden chills, fever, back pain, shortness of breath, fatigue, irritability, can also be nausea, vomiting, abdominal pain gastrointestinal symptoms. yes a lot of intravascular hemolysis, hemoglobinuria can occur, urine samples Secheng strong tea or soy sauce, and accompanied by mild jaundice, abnormal blood case of transmission error caused by hemolysis may occur oliguria, anuria and acute renal failure. In severe acute hemolysis, patients with anemia, hypoxia may appear indifferent consciousness, coma, shock and cardiac insufficiency. in patients with chronic hemolytic anemia and jaundice can be a sudden increase, known as the acute crisis. The reason often associated with poisoning, repeated infection and other factors. Clinically, acute hemolytic crisis can have three different types. (1) crisis aplastic anemia (aplastic crisis): the most common. its pathogenesis as a red blood cell regeneration moment of failure. Clinically, aplastic crisis usually presents a sudden drop in reticulocytes, anemia, increased sharply. marrow cytology may have 2 main types: few nucleated red blood cells, or even completely missing. only to see the grain in the bone marrow Department and the giant nuc
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