Administration of different doses and methods of clinical efficacy of methotrexate treatment of ectopic pregnancy.docVIP

 PAGE \* MERGEFORMAT 7 Administration of different doses and methods of clinical efficacy of methotrexate treatment of ectopic pregnancy [Keywords: means different dose clinical efficacy of methotrexate ectopic pregnancy The past 10 years, the incidence of ectopic pregnancy increased significantly compared to become one of Obstetrics and Gynecology common acute abdomen; same time as the treatment technology, the early diagnosis of ectopic pregnancy rate much higher than before. Ectopic pregnancy, drug treatment may be waived surgery, to retain the integrity of the structure and function of oviduct in the early treatment of ectopic pregnancy more and more important. now our hospital administration of different doses of different ways of early ectopic pregnancy with methotrexate treatment of 225 cases to analyze the clinical efficacy and side effects. 1 Materials and Methods 1.1 General Information January 2003 ~ January 2008 were treated in our hospital 225 cases of early unruptured ectopic pregnancy, the average age of 25.00 + -4.2 years old, the average time of 50.00 + -6.05 menopause days. Methotrexate treatment indications: ① no drug treatment taboos; ② ruptured ectopic pregnancy or miscarriage does not occur; ③ pregnancy mass diameter lt;4 cm; ④ serum β HCG lt;2000u / l; ⑤ no significant internal bleeding. 1.2 Methods 225 patients were hospitalized, were randomly divided into 3 groups of 75, the average age of menopause, time, mass, diameter, pre-treatment levels of serum β  HCG was no significant difference. A group given methotrexate 0.4mg / kg.d intramuscular injection for 5 days for one course; B group methotrexate 1.0 mg / kg.d intramuscular injection, 1-day course of treatment; C Group methotrexate 1.0 mg / kg.d intramuscular injection every other day 1, shared 4 times, every other day intramuscularly folate 0.1 mg / kg.d detoxification. medication during the application of quantitative serum β HCG and B-to closely review care: i