Aidi injection on the cellular immune function in patients with colon cancer effect.docVIP

 PAGE \* MERGEFORMAT 3 Aidi injection on the cellular immune function in patients with colon cancer effect [Abstract] Objective: To Aidi injection before and after treatment NK cells and T cell subsets in detection of colon cancer cells of their immune function. Methods: The flow cytometry detected 50 cases of colon cancer patients and 20 patients with normal NK cells and T cell subsets. Results: The tumors of patients with NK cell activity, percentage, CD3, CD4, CD4. CD8 were significantly reduced; the use of Aidi injection treatment, and all targets were significantly increased. Conclusions: Aidi injection can significantly enhance the cellular immune function in patients with colon cancer. [Keywords:] cell-mediated immunity; Aidi injection; colon cancer; immune function Since July 2005 ~ June 2006, we adopted the observation of patients with colon cancer in the application of traditional Chinese anticancer drugs Aidi injection before and after the NK cells and T-cell subsets and identify their impact on immune function in patients with a better understanding of its clinical value. 1 Data and methods 1.1 Case Selection tumor group of 50 patients, male 38 cases, 12 females; aged 43 to 80 years, mean 52.5 years old; in which 33 cases of colon cancer, rectal cancer, 17 cases were confirmed by pathological examination. The control group, 20 cases of normal healthy people, 16 males and 4 females; aged 40 to 76 years, with an average 51.2 years of age. 1.2 Detection of NK cell activity using cytoplasmic lactate dehydrogenase release assay, T lymphocyte subsets, NK cell percentage using FACS-Calibur flow cytometer, Simulsetv3.1 analysis software. 1.3 treatment group at the first detection of cancer, will Aidi injection 400ml in 40ml normal saline infusion day 1, 14d for a course of treatment. Review of NK cells and T-lymphocyte subsets. 1.4 Toxicity to monitor whether the abnormal reaction during the medication, check before and after treatment of bl