Alismataceae role of lipid-lowering pharmacological and material progress of basic research.docVIP

 PAGE \* MERGEFORMAT 6 Alismataceae role of lipid-lowering pharmacological and material progress of basic research [Keywords:] Alismataceae; blood cholesterol; material basis for Dirty, and in which to break it down metabolism, and is able to inhibit plaque formation [3]. Alisma aqueous extract, ethanol extract of lipid-lowering effects. Showed that water extract of Alisma orientalis, alcohol extract can significantly reduce the obese mouse model of serum TC, TG concentrations, increased HDL-C concentration, both on lipid metabolism in the pros and cons no significant difference in [4]. Alismataceae affect current study focused on lipid metabolism in the fat-soluble components, there are experiments in water-soluble components Alisma tips also has a good lipid-lowering effect. Chen-Hui Li et al [5] observed Alisma Decoction on rat serum and liver homogenate lipid content, bile flow and its components affect the results showed that large doses of Alisma Decoction could significantly reduce serum total cholesterol, low - density lipoprotein, liver homogenate total cholesterol and triglyceride levels, increase bile flow, bile cholesterol, increasing the total amount at the same time, but also increase the cholesterol-solvent total bile acid and phospholipid content. 2, the chemical constituents of Alisma orientalis So far, isolated from Alisma more than 60 kinds of compounds, of which there are more than 30 kinds of Alisma alcohol. Alisma Triterpenoid compounds are: Alisol A, Alisol A-24-acetate, alisol B-23-acetate, epialisol A, 11 - deoxy-Alisol A , alisol C, Alisol C-23-acetate, 16,23 - oxidation Alisol E, Alisol F, Ali and Ali Alisol Alisol A former B-type tetracyclic 3 terpanes terpenes [6]. Alisma in sesquiterpene compounds, most of Guaiacyl alkane type, extracts from Alisma lipophilicity part of the separation of orientalolA, B, C, from the water-soluble part of the separation of four sesquiterpenes sulfoorientalolA, B, C, D [7]. Alismataceae also conta