Aripiprazole and risperidone in the treatment of schizophrenia 1.docVIP

 PAGE \* MERGEFORMAT 4 Aripiprazole and risperidone in the treatment of schizophrenia 1 Authors: LIU Chong-yang, WANG Yong, Wen-Te Liu, Zheng-Rong Liu [Abstract] Objective To evaluate aripiprazole in the treatment of schizophrenia and adverse reactions. Methods 90 patients with schizophrenia were randomly divided into two groups were treated with aripiprazole and risperidone in the treatment of 8 weeks to conduct an open controlled study. Using Positive and Negative Syndrome Scale (PANSS). Treatment Emergent Symptom Scale (TESS) assessed the efficacy and adverse reactions. The results of efficacy and adverse reactions between the two groups was no significant difference, but risperidone group body mass gain, galactorrhea, amenorrhea or delayed menstruation slightly higher than the aripiprazole group. Conclusion aripiprazole and risperidone in the curative effect is similar to body mass gain, galactorrhea, amenorrhea or delayed menstruation less than risperidone is an effective and safe antipsychotic. [Keywords:] Aripiprazole; risperidone; Schizophrenia With aripiprazole (trade name: brisking) and risperidone (brand name: Risperdal) in the treatment of schizophrenia, comparing the efficacy and safety of the two drugs. 1 Data and methods 1.1 targeted at our hospital in August 2006 -2007 years in October out-patient or hospitalized patients, in line with the Chinese Classification and diagnostic criteria for mental disorders third edition of the diagnostic criteria for schizophrenia; Positive and Negative Syndrome Scale (PANSS) score ≥ 60 points; routine blood, urine, chest X-ray, liver function, electrocardiogram, blood glucose Deng Jun normal. Excluding alcohol and drug dependence, organic diseases. A total of 90 patients were randomly divided into two groups. Aripiprazole group of 45 cases, male 25, female 20 cases; aged 17 to 50 years old on average (30.7 ± 8.7) years; the average duration (18.9 ± 11.3) months. Risperidone group of 45 cases, male 22 c