Assay preparation Shengmai Research Progress.docVIP

 PAGE \* MERGEFORMAT 21 Assay preparation Shengmai Research Progress Abstract overview of relevant domestic Shengmai assay of the preparation research, in order to enhance and improve the health pulse agents provide the basis for quality control system, while allowing a variety of pharmaceutical workers, according to the actual situation choose to apply. Keywords: Shengmai; Determination; Research “Shengmaisan” of the party were the first element contained in the book Zhang Jin and Yuan Dynasties “medical Qi Yuan” (1186), formed in the “theory within the trauma straighten out confusing” and perfecting the “medical side test,” [1,2] . “Medical Qi Yuan” in the records, the party from ginseng, Ophiopogon, Schisandra composition. Attending debilitating heat, Yinyekuihao of Qi and Yin Deficiency Syndrome. In the modern science and technology, driven by Shengmaisan also developed for a number of modern new formulation, its set of square has also changed. For example, by the substitution ginseng red ginseng and Ophiopogon, Schisandra composition Shengmai injection [3]; get rid of Schisandra, only the composition of ginseng and Ophiopogon japonicus Shenmai injection, etc. [4]. The emergence of a variety of formulations for the quality of Shengmai agents have higher requirements, but there is no ShengmaiYin determination in the Pharmacopoeia entry [3,5]. Therefore, the author of the recent literature related to tracking, sorting and classification of Shengmai agents wish to contribute to the research and control of quality standards, in particular the determination of the improvement and perfection. Now Shengmai assay of the preparation studies as summarized below. A high-performance liquid chromatography 1.1 ginseng saponins Li Jie et al [6] were determined using HPLC method of ginsenoside ShengmaiYin Rb1, Rb2, Re content. Methods: LC-4A high-performance liquid chromatography, YWG-C18 (5 μm, 4.6 mm × 250 mm) column, mobile phas