Austria - Lumbrokinase for non-plasma endothelin in patients with unstable angina pectoris and left ventricular diastolic function in.docVIP
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Austria - Lumbrokinase for non-plasma endothelin in patients with unstable angina pectoris and left ventricular diastolic function in
Abstract Objective: To observe the oral administration of 100 Austrian lumbrokinase (Beijing 100 Olympic Pharmaceutical limited liability company production) of non-plasma endothelin in patients with unstable angina pectoris and left ventricular diastolic function. Methods: 80 patients with unstable angina were randomly divided into two groups, one group of conventional treatment group (A group), another group on the basis of the above-mentioned treatment was added 100 Austrian Lumbrokinase oral (B group), observation the two groups before and after treatment of plasma endothelin and left ventricular diastolic function changes. Results: After treatment, plasma endothelin decreased (P lt;0.01), left ventricular diastolic function were improved (P lt;0.01 or P lt;0.05), but the B group improved more significantly (P lt;0.01 or P lt;0.05). Conclusion: The 100 Olympic lumbrokinase in patients with unstable angina can reduce plasma endothelin levels, and can improve the left ventricular diastolic function.
1 Materials and Methods
1.1 The clinical data collection in January 1996 ~ March 1999 during the period of hospitalization in patients with unstable angina pectoris 80 cases (both in line with the standards set by the World Health Organization, 1979), of which 59 cases of male and female 21 cases: Age 42 ~ 69 years old, with an average 56.4 ± 10.1 years, with the initial issuance of angina pectoris in 23 cases, worsening angina pectoris 41 cases, 16 cases of mixed angina pectoris. After admission all patients were given creatine kinase-side (ck) and its isoenzyme (ck-mb), to rule out acute myocardial infarction.
1.2 treatment of 80 cases of unstable angina were randomly divided into two groups, A group for the conventional treatment group, namely, static points, nitrog
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