Children 21 cases of renal tubular acidosis Misdiagnosis.docVIP

 PAGE \* MERGEFORMAT 7 Children 21 cases of renal tubular acidosis Misdiagnosis [Keywords:] renal tubular acidosis, misdiagnosis Renal tubular acidosis (renal tubular acidosis, RTA is a group of different causes of renal tubular excretion back to H + and HCO-3 absorption of uric acid of the damage occurred obstacle to high-acidosis as the main clinical manifestations of disease [ 1]. RTA is not uncommon in clinical practice, but its lack of specificity, often misdiagnosed. Early treatment can prevent recurrence of child as a result of metabolic acidosis, growth retardation, osteoporosis, bone deformities and even fractures, severe kidney calcification complications. our hospital in October 1995 ~ June 2008 21 cases of misdiagnosis of renal tubular acidosis, as follows. 1 Clinical data 1.1 General Information The group of 21 patients, 16 males and 5 females, aged 32 days to 12 years old, 9 patients aged 0 to 1, 1 to 3 years and 6 cases, 4 cases 3 to 6 years old, 6 to 12 years old 2 cases. onset age of 18 days to 11 years, the shortest duration of 12 days, up to 8 years. visits to the diagnosis of the shortest 23 days, up to 1 year. lagged behind the growth of clinical manifestations in 18 cases, 11 cases of skeletal deformities, muscle weakness 7 cases, fracture in 1, nausea, vomiting, feeding difficulties in 6 cases, polydipsia and polyuria in 2 cases, arrhythmia in 2 cases. 1.2 The auxiliary examination of 19 cases of metabolic acidosis, anion gap were (AG) abnormally high chloride metabolic acidosis. PH decompensation (lt;7.3518 cases, compensation in the normal range (7.35 ~ 7.453 cases. Hypokalemia 18 cases, 2 cases of hyponatremia, blood glucose, normal serum creatinine and blood urea nitrogen, urine pH5.5 ~ 8.0 (18 例 urinary pHgt; 6.0), kidney stones ultrasound found in 17 cases, 2 cases of renal calcification in 2 cases, renal increased echo in 4 cases. skeletal X-ray in 11 patients with active signs of 9 cases of rickets, skeletal age beh