Children Liyan Granules in mice and rabbits antipyretic analgesic effect of experimental observation of.docVIP

 PAGE \* MERGEFORMAT 4 Children Liyan Granules in mice and rabbits antipyretic analgesic effect of experimental observation of Author: Zhang Xin, Song Yi, Wang Shi, Yong-Lin Liu, Zhang Ye, Zhang [Abstract] Objective To observe the children Liyan Kang granule on experimental animals antipyretic analgesic effect. Methods The children observe the hot-plate test in mice Liyan Granules pain threshold values, application of typhoid vaccine-induced fever was observed in children Liyan Granules of rabbit fever reaction in vivo. Results gavage for children Liyan Granules 60 min each dose group were generated after the analgesic effect of the intravenous injection of typhoid vaccine-induced fever in rabbits significantly inhibited. Conclusions Pediatric Liyan Granules in experimental animals have significant antipyretic and analgesic effect. [Keywords:] Children Liyan Granules; antipyretic analgesic; animal experiments Clinical acute and chronic pharyngitis and tonsillitis are children of the more common causes of fever, one of [1]. Children Liyan Granules by Yu-chu, puerarin, Anemarrhena, Ophiopogon japonicus and other traditional Chinese medicine composed by clinical observation of children’s acute and chronic pharyngitis and tonsillitis there is a certain effect, with heat-clearing and detoxifying, anti-inflammatory pain, the efficacy of Qi phlegm . To further confirm the pharmacological effect and its mechanism, this study conducted a series of animal experiments. Children now Liyan Granules antipyretic analgesic effect of experimental study reported below. 1 Materials and methods 1.1 medicines in children Liyan Kang granules (990,715, non-concentrated liquid additives containing health dose 2 894.7 g / L), provided by the China Medical University (hereinafter referred to granules); throat Ji Ling Capsule (981,004) from Tianjin America Lun Pharmaceutical Co., Ltd. production; of aspirin (990,418) from Shenyang Medical College production; typhoid vaccine (9101)