Children with Helicobacter pylori associated gastritis peptic ulcer treatment and drug resistance.docVIP

 PAGE \* MERGEFORMAT 15 Children with Helicobacter pylori associated gastritis peptic ulcer treatment and drug resistance Study: white plant peak, Wu Xiaoxia, Jin Guoxin [Abstract] Objective?: The children in our hospital found that Helicobacter pylori infection (HP) the resistance to antibiotics in order to guide the choice of anti-HP treatment. Methods: 183 patients presented with symptoms of upper gastrointestinal endoscopy in children with the line inspection, at the same time rapid urease test (RUT) and histology staining to find HP to understand the HP infection, and further separation of the line HP, culture, identification, understanding of HP in vitro drug resistance. for testing and RUT were positive for HP stained tissue sections The children were randomly divided into two groups, respectively, omeprazole + amoxicillin + furazolidone and omeprazole + clarithromycin + metronidazole triple regimen 2 weeks, repeated endoscopy 4 weeks after drug withdrawal and HP RUT, stained tissue sections in order to understand the effect. Results: Omeprazole + amoxicillin + Furazolidone treatment group more effective than omeprazole + clarithromycin + metronidazole group (P lt;0.01); vitro HP susceptibility test results showed that the antibiotic resistance rates were significantly different (P lt;0.01), to clarithromycin, metronidazole resistance was higher, while the most sensitive to amoxicillin, and furazolidone, Qing Trappe hormone resistance rates relatively low. Conclusions: HP-related chronic gastritis, peptic ulcer in the choice of anti-HP recommended use of antibiotics or gentamicin ī??? furazolidone. [Keywords:] children; Helicobacter pylori; resistance; chronic gastritis Many studies indicate that chronic gastritis, peptic ulcer disease and gastrointestinal Helicobacter pylori (HP) infection is closely related. In addition to the traditional inhibition of gastric acid, gastric mucosal protection, the use of antibiotics in the treatment of HP i