Children with severe erythema multiforme clinical analysis of 10 cases.docVIP

 PAGE \* MERGEFORMAT 12 Children with severe erythema multiforme clinical analysis of 10 cases 【Abstract】 Objective To improve the severe erythema multiforme clinical knowledge to improve the cure rate. Methods Retrospective analysis of 10 cases of erythema multiforme in children with severe clinical symptoms and laboratory data, in the symptomatic treatment based on the support given to the impact of methylprednisolone plus gamma globulin treatment. Results 10 cases of children with severe erythema multiforme are the typical clinical manifestations, mucosal involvement heavier treatment 10 d after the rash scab, no pigmentation. Conclusion The early impact of methylprednisolone combined with high-dose gamma globulin can improve the severe erythema multiforme cure rate and reduce complications. Keywords: severe nature of erythema multiforme / drug therapy; Methylprednisolone / therapeutic use; gamma globulin / therapeutic use; children , Also known as erythema multiforme exudative erythema multiforme, is a group involving the skin and mucous membrane, manifested as erythema, papules, and blisters skin and mucous membrane damage such as acute, self-limiting and often recurrent disease. The less severe erythema multiforme and less incidence of recurrence, easily misdiagnosed, now undergraduate since 2000  01 ~ 2008  10 children admitted to 10 cases of severe summarized as follows reported. A clinical data 1.1 General Information 10 cases admitted to hospital pediatric wards with severe erythema multiforme in children in the 4 males and 6 females; aged 4 to 12 years old, with an average 6.5 years old; are in line with literature [1] diagnostic criteria. Children were 10 cases of sudden onset, fever, skin rash associated with the same time, prior to the onset of 4 cases have a clear history of medication, 2 patients taking phenytoin, and 1 case took Daqingye compound mixture, and 1 take Chinese medicine. 10 cases of children,