Children with viral respiratory tract infection antiviral treatment.docVIP

Children with viral respiratory tract infection antiviral treatment.doc

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 PAGE \* MERGEFORMAT 12 Children with viral respiratory tract infection antiviral treatment [Keywords:] children with viral respiratory tract infection antiviral treatment Acute respiratory infections are common diseases of children, viral infections, in which an important proportion. As the virology, molecular biology, clinical pharmacology study of such disciplines as the development and progress, people can be diagnosed through a variety of advanced technology and viral infections, but also there are always new and effective antiviral drugs has been the development and utilization of certain childhood Common viral respiratory infections can get timely and effective diagnosis and treatment. A human respiratory syncytial virus, human metapneumovirus infection Human respiratory syncytial virus (human respiratory syncytial virus, hRSV) is a respiratory tract infection in children, especially infants and young children with acute lower respiratory tract infection the first viral pathogen. Has so far no specific measures for prevention and treatment of hRSV. Clinical application of more drugs ribavirin (Ribavirin). Ribavirin belongs to nucleoside-type drugs, is a broad-spectrum antiviral drug, in vitro inhibit a variety of DNA and RNA virus replication, the mechanism is unclear. It currently considered A and B influenza viruses, parainfluenza viruses, adenoviruses, RSV, herpes simplex virus (HSV), measles virus, varicella-zoster virus, mumps virus are inhibited. In 2003 severe acute respiratory syndrome (severe acute respiratory syndrome, SARS) epidemic during this drug in combination with methylprednisolone, but also observed that its SARS coronavirus (SARS  CoV), or that have a certain effect of SARS virus infection. General use 10 ~ 15 mg / (kg * d), severe 30 ~ 40 mg / (kg * d). Oral medication may have gastrointestinal reactions, dizziness, skin rash, high-dose intravenous administration can cause leukopenia, anemia, immune suppression and liver dysfu

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