Chlordimeform acute poisoning (severe) clinical analysis of 21 cases.docVIP

 PAGE \* MERGEFORMAT 8 Chlordimeform acute poisoning (severe) clinical analysis of 21 cases [Abstract] Objective: To explore the incidence of pesticide poisoning chlordimeform mechanisms, clinical features and treatment measures. Methods: Over the past 10 years, hospitalized with acute chlordimeform received severe pesticide poisoning 21 patients in its clinical manifestations, and treatment method of the inspection findings and analysis. Results: Chlordimeform severe pesticide poisoning in 21 cases, the cured 16 cases, 5 cases died, the mortality rate reached 23.8%. Conclusion: The poisoning mechanism is direct inhibition of in vivo monoamine oxidase and acetyl-converting enzyme, its metabolites on the body can cause serious damage. The main clinical manifestations with disturbance of consciousness, cyanosis, and hemorrhagic cystitis into three syndrome. In the treatment of measures, should be completely rid of as soon as possible and application of methylene blue poison antidote. Severe damage and often complicated by multiple organ failure, fatal complications of brain edema, respiratory failure, and so should be a timely manner. [Keywords:] chlordimeform; poisoning; rescue; Analysis Chlordimeform pesticide poisoning with severe multi-system damage, prone to cause multiple organ failure. To improve the success rate of resuscitation of severe poisoning chlordimeform. Our hospital from January 1997 ~ December 2007 Statistics of the 33 cases of acute poisoning chlordimeform, of which 21 cases of severe, moderate and severe cases of treatment now the situation is as follows: A clinical data 1.1 General Information Chlordimeform in 21 cases of acute severe poisoning in 8 males and 13 females, aged from 18 to 62 years. All cases were caused by oral poisoning, of which 12 cases of poison reaches 250 ~ 500 ml,, poison to the rescue time is 20 min ~ 4 h, an average of 76 min. 1.2 Clinical manifestations Due to poison consumption, a rescue is not timely, mor