Chronic Fatigue Syndrome Research neuroendocrine mechanisms.docVIP

 PAGE \* MERGEFORMAT 17 Chronic Fatigue Syndrome Research neuroendocrine mechanisms [Keywords:] chronic fatigue syndrome, neuroendocrine, hypothalamus - pituitary - adrenal axis, neurotransmitters Neuroendocrine changes in chronic fatigue syndrome is considered (Chronic fatigue syndrome, CFS) a common mechanism of various risk factors. Among them, the hypothalamus - pituitary - adrenal axis (hypothalamic-pituitary-adrenal axis, HPAA) function decline and 5 - HT (5-HT) neurotransmitter function of the central nervous system disorders such as play a major role, while growth hormone (growth hormone, GH), melatonin (melatonin, MT), etc. may also be abnormal secretion of pathogenesis. but on These changes in the pathogenesis of the specific role played by still controversial, pending further research. Chronic fatigue syndrome is a kind of sustained, relapse is characterized by debilitating fatigue, accompanied by other physiological disorders and psychiatric symptoms of the syndrome. Although the pathogenesis of this syndrome is still not completely clear, but generally considered immune disorders and neuroendocrine and other potential factors. which, cortisol, neurotransmitters and changes in the interaction between various risk factors is seen as a common way. This article from the hypothalamus - pituitary - adrenal axis ( HPA) and central neurotransmitter function such as changes to aspects of CFS, are reviewed. 1 infection and CFS The current study, CFS incidence of viral infection with a particular. CFS occasionally occur in infectious mononucleosis and after the prevalence of high titers of serum anti-EBV antibodies, suggesting that EBV infection may be the cause of CFS A. Lener et al [1] l6 cases in 2002 contains a higher serum titer of anti-EBV VCA antibody and / or anti-EA antibodies in CFS patients with diffuse for 6 months of acyclovir therapy, achieved significant efficacy support the role of EBV in the pathogenesis of CFS. However, some r