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Cirrhosis of the liver and small intestine bacterial overgrowth
Keywords: cirrhosis intestinal bacterial
In patients with gastrointestinal bleeding due to cirrhosis of the liver, bile acids and the relative lack of gastric acid, intestinal movement disorders and other factors, could lead to an increase in aerobic intestine and colon bacteria migrating to the jejunum and duodenum, causing intestinal bacterial overgrowth growth (small intestinal bacterial overgrowth SIBO). With jejunal or duodenal fluid bacterial culture, colony number of adultsgt; 105/ml, childrengt; 104/ml as the standard [1]. Subsequently developed intestinal absorption dysfunction, malnutrition, increased endogenous infections (ie bacteria invade the body from the intestinal mucosa near the local organization or body fluids, thus into the blood and other body parts) and endotoxemia opportunities. Endogenous infection and endotoxemia in liver damage is further aggravated. The authors in recent years, studies related to SIBO patients with cirrhosis are reviewed.
A micro-ecological changes in cirrhosis SIBO
Most of the human gut microbes in the anaerobic genus Bacteroides, Escherichia coli and Enterococcus, Lactobacillus, and type diphtheria bacilli are also common. From the small intestine to the colon, with the total number of bacteria down the intestine also increased [2]. Intestinal origin bacteria, especially anaerobic bacteria such as Bifidobacterium, Lactobacillus and so has the nature of planting and breeding has played the role of bio-barrier can prevent the foreign flora in the gut colonization and reproduction. Patients with liver cirrhosis colon bacteria shifted to the small intestine. Environment Staphylococcus aureus and Candida albicans colonization, etc., into the small intestine, the hospital environment, pathogenic bacteria such as Pseudomonas aeruginosa and a number of conditions, producing ultra-broad-spectrum enzyme (ESBL) in
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