Chronic renal insufficiency serum enzyme changes and clinical significance of.docVIP

 PAGE \* MERGEFORMAT 3 Chronic renal insufficiency serum enzyme changes and clinical significance of Author: Zhang Zhongxian ZHOU Fu-Ming Wei de l art LEE Yuk Hing Fei Xue-Feng Zhang [Keywords:] chronic renal failure serum enzyme Chronic renal failure (CRF) is a variety of end-stage renal disease developed into a serious stage, the authors found that in clinical practice, several common serum enzymes [1]: lactate dehydrogenase (LDH, LD), A-hydroxybutyrate acid dehydrogenase (HBDH, HBH), aspartate aminotransferase (GOT, AST), alanine aminotransferase (GPT, ALT), creatine kinase (CPK, CK), creatine kinase isoenzyme (CK-MB), alkaline phosphatase (ALP), amylase (AMY, AMS) abnormal increase; these enzymes, while not unique to kidney disease, but the changes in CRF Shique exception occurs, the author aims to analyze as a important component of cellular enzymes in the progress of renal disease in the changes in the CRF to determine the clinical severity of the disease to provide diagnosis. A clinical data 1.1 General Information Choose from January 2006 to October 2008 in-patient and outpatient, a total of 120 cases, male 58 cases, female 62 cases; meet the diagnostic criteria for CRF [2], to exclude the determination, liver, pancreas and other primary diseases, and were divided into four groups according to renal function in each group were three indicators of access to renal replacement therapy before. Table 1. Table 1 CRF patient sex, age and duration of composition (abbreviated) 1.2 Methods Fasting venous blood collected 3ml. 2h Neice complete separation of serum, using Hitachi 7180 automatic biochemical analyzer. LDH, HDBH, CK, CK-MB, AST, ALT, ALP with Shanghai Shenergy’s kit, and method for the continuous monitoring method. AMS uses iodine, starch, colorimetry, according to the national standard operating procedures for operation. 1.3 CRF diagnostic criteria and disease classification standard Reference: Wang Haiyan, ‘Nephrology’, 2nd edition [2]. (1)