Cirrhosis with portal hypertension before and after splenectomy and treatment of changes in platelet.docVIP

 PAGE \* MERGEFORMAT 5 Cirrhosis with portal hypertension before and after splenectomy and treatment of changes in platelet Author: Lo King-mao, Liang Chong, Wen-Hai, Huang Yingying [Abstract] Objective To investigate the portal hypertension after splenectomy platelet (PLT) change in the number of clinical significance. Method of statistical analysis of 153 cases of cirrhosis of the liver with splenomegaly hypersplenism before and after splenectomy in patients (cirrhosis group) PLT count and liver function was observed trends PLT, PLT compare changes before and after splenectomy and liver function changes in relationships, and spleen trauma group comparison. Results Most patients with liver cirrhosis group increased PLT, some do not rise, or even lower, and with liver function-related. Liver cirrhosis group than in the trauma group before and after surgery PLT did not change significantly. Conclusion cirrhosis of the liver to reduce the number of PLT addition to splenomegaly and other related reasons, but also may be related to changes in liver function. [Keywords:] liver cirrhosis; Hypertension, portal; Splenectomy; platelet count Cirrhotic portal hypertension is often accompanied by ‘splenomegaly’ and ‘hypersplenism’, showed blood cells for at least three lines of a series of unusual or significantly reduced, most patients with platelet (PLT) significantly reduced as the main performance. In the past that the spleen caused by portal hypertension in patients with cirrhosis may be hyper-reactive PLT decline can be attributed, by surgery (splenectomy from broken blood vessels around the cardia surgery), or transjugular intrahepatic portosystemic shunt portal pressure reduction after more than hypersplenism eliminate, PLT quantity back to normal. But in recent years studies have shown that clinical practice [1] Some patients can not meet the latter two, and some blood cells in patients after splenectomy, especially the PLT did not rebound, or even lower. The