Clinical characteristics of different age groups of systemic lupus erythematosus.docVIP

 PAGE \* MERGEFORMAT 14 Clinical characteristics of different age groups of systemic lupus erythematosus Of: WANG Hai-ying Li Wuping clouds Fish [Abstract] Objective To investigate the age of systemic lupus erythematosus (systemic lupus erythematosus, SLE) clinical features. Way statistical analysis of 550 patients SLE patients (102 cases in which elderly group, 415 cases of adult, children 33 cases) the clinical manifestations and laboratory indicators and controls. Results elderly group F: Male to 5.38:1, adult female: male was 11.2:1, Junior Female: Male to 7.25:1, the average time of onset to diagnosis in the older adult group leader children group was significantly shorter than the adult group, age group fatigue, joint pain, weight loss, muscle weakness, lung disease more common. Children weight loss, kidney damage, skin rashes, neurologic disorder more common. old age group increased ESR fast, liver dysfunction more common, complement reduced, dsDNA-positive rate was significantly lower than the adult group (P lt;0.025). Children U1RNP, dsDNA-positive rate, IgG increased, anti-Sm-positive rate (P lt;0.05). Conclusion elderly and children, clinical manifestations of SLE, is not typical of misdiagnosis and missed diagnosis. elderly SLE Raynaud’s phenomenon, alopecia, low incidence of renal damage, less severe, the prognosis is good, children SLE kidney damage, neuropsychiatric symptoms were more common, the condition weight, rapid development and poor prognosis. [Keywords:] systemic lupus erythematosus clinical features of different ages Systemic lupus erythematosus (systemic lupus erythematosus, SLE) is a violation of multi-system and multi-organ autoimmune disease, its incidence in different age, gender, race and region significantly different [1]. Prevalent in the growth of women, the elderly and children is less common. Compared with adults, the elderly and children in clinical and laboratory SLE have their own characteristics. domestic and