Clinical deep fungal infection and drug resistance analysis of.docVIP

 PAGE \* MERGEFORMAT 10 Clinical deep fungal infection and drug resistance analysis of Author: Song Xin Zhi-Gang Jin Qin tube dove Keywords: fungal infection Deep fungal infection known as invasive fungal infection, occurring mainly in hospitals. In recent years, due to broad-spectrum antibiotics, immunosuppressive agents, and the application of corticosteroids, organ transplantation, radiation therapy and other treatment techniques to carry out, the increasing number of clinical fungal infections, has become one of the common pathogens of nosocomial infection; the same time, anti-fungal infection treatment or preventive therapy has led to drug resistant strains [1]. In order to understand the clinical hospital of deep fungal infection and drug resistance is now right for inspection in 2006 clinical specimens isolated from deep fungi and susceptibility results were retrospectively analyzed, the report is as follows. 1 Data and methods 1.1 Strain Source January to December 2006, from the hospital to retain an infection of the specimen (sputum, throat swab, urine, stool, blood, secretions, gastric, pleural effusion, cerebrospinal fluid, drainage fluid, pus, intravenous catheter) isolated from the deep mycoses. 1.2 Instrument and reagents Using chromogenic medium Candida French Kema Jia (Zhengzhou Institute of Biotechnology Bossay-packing), VITEK automatic micro-analyzer and YBC identification card, the French company bioMérieux, modified Shadomy agar, econazole (ECO) , nystatin (NYS), clotrimazole (CTR), ketoconazole (KET), fluconazole (FCZ), itraconazole (ITR) sensitivity paper, Denmark, Rosco company. 1.3 Methods Fungal specimens were identified by conventional methods of immunization in the Kema Jia Candida chromogenic culture medium, after 24 ~ 48 h 35 ℃ culture, the emergence of various colors colonies, the smears, staining, according to product instructions on the criteria for judging Identi