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Clinical Analysis of 15 cases of Crohn#39;s disease
【Key Words】 Crohn symptoms and general pathology digestive endoscopy
Crohn’s disease (Crohn, CD) is an unknown etiology of the digestive tract with chronic granulomatous inflammatory disease, more common in Western countries, the domestic is relatively rare, but a rising trend in recent years, diverse clinical manifestations, disease complex. Clinically, abdominal pain, diarrhea, abdominal mass, fistula formation and intestinal obstruction characterized, can be accompanied by fever, anemia, nutritional disorders and joints, skin, eyes, oral mucosa, liver and other parenteral damage. Recurrence of this disease are life-long tendency to severe persistent unhealed patients with a poor prognosis. From 2002 to 2008 in our hospital received a total of 15 cases of CD patients are reported as follows.
A clinical data
1.1 General information on 15 cases of CD patients, male 10 cases, female 5 cases, male: female 2:1. Aged 15 to 62 years, with an average 38.5 years old, 20 years of age in 2 patients, 21 ~ 49 years old in 22 cases, 50-year-old more than 4 cases. Time of onset to diagnosis was 3 days to 4 years (mean 11 months). 7 cases in which surgical treatment, non-surgical treatment in 8 cases, 15 cases were characterized by pathology, surgery, or endoscopy and X-ray barium meal a clear diagnosis, all in compliance with WHO diagnostic criteria for Crohn’s disease.
1.2 site and incidence of clinical manifestations of disease prevalent in the terminal ileum and adjacent colon, but sections of the digestive tract mouth to anus may be involved, showed segmental or leap distribution. To a maximum of ileum are violated, 9 patients (60%), small bowel in 4 cases (26.7%), colon in 2 cases (13.3%). The vast majority of patients with abdominal pain (14 to 15,93.3%), to have lower abdominal pain, followed by Cullen pain and abdominal pain are not clear or part of those
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