Compound Pueraria capsule of the acute toxic effects.docVIP

 PAGE \* MERGEFORMAT 8 Compound Pueraria capsule of the acute toxic effects Study: Pan Hongping, Yang Jiazhen, Hua Wei Ling, Zhong Zhengxian, Chen Xuefen, Li Yan Jing [Abstract] Objective To observe the effects Pueraria capsules acute toxicity. Methods compound with the greatest concentration of Pueraria capsules and the maximum volume of liquid administered oral administration, the control group received the same volume of distilled water, 3 times / d. 14 continuous observation d, the mice toxicity. Results observed 14 d after the treatment group compared with the control group, all animals kept healthy control group and treatment group the average increase of body weight in mice was 40.56%, 40.96%, no significant difference (Pgt; 0.05, no any toxic reaction. calculate the maximum amount of 2 322 mg dose puerarin / kg body weight. Conclusions less toxic compound Pueraria capsule. [Keywords:] Compound Pueraria capsule, Pueraria, acute toxicity in mice Abstract: ObjectiveTo study the acute toxicity of Compound Pueraria extract capsule on mice. MethodsMice in experimental medicine group were intragastrically administered Compound Pueraria extract capsules by the thickest concentration and the largest volume permitted three times one day, and were observed on the situation of acute toxicity in the successive 14 days. Mice in control group were administered the equal distilled water and were conducted with the same methods as the experimental medicine group.ResultsCompared with the control group, all mice in the experimental medicine group survived healthyly and the increasing rates of weight in the two groups were respectively 40.56% and 40.96% (Pgt; 0.05). No acute toxicities were observed in both groups. The largest dose of compound pueraria extract capsule was 2322 milligram of puerarin per kilogram in mice.ConclusionCompound Pueraria extract capsule has little acute toxicity in mice. Keywords:: Compound Pueraria extract capsule Pueraria lobata (