Compound Yigan Tablets silybin by High Performance Liquid Chromatography.docVIP

 PAGE \* MERGEFORMAT 7 Compound Yigan Tablets silybin by High Performance Liquid Chromatography [Abstract] Objective To establish the compound Yiganling Tablets silybin method for the determination. Methods HPLC method, ODS C18 (4.6 mm * 250 mm, 5 μ m), with methanol - water - glacial acetic acid (48:52:1) as mobile phase, flow rate 1.0 ml * min-1, detection wavelength 287 nm. Results silybin in the 13.75 ~ 110.00 μ g * ml-1 within the concentration range of the sample with peak area showed good linear relationship (r = 0.999 8), the average recovery was 97.10% (RSD = 0.63%, n = 6). Conclusion The method is simple, reliable, reproducible, and can be used in compound Yigan Tablets silybin analysis. [Keywords:] high-performance liquid chromatography compound Yigan Tablets silibinin Abstract: ObjectiveTo develop a method for determining the content of Silymarin in Fufang Yiganling tablets. MethodsHPLC analysis was carried out at the following conditions: Cromasil C18 column (4.6 mm * 250 mm, 5 μ m), mobile phase: Methanol-Water-Acetic acid (48:52:1), the detection wavelength was at 287 nm the flow rate was 1.0 ml * min-1. ResultsThe standard curve was linear over the range of 5.9 ~ 29.5 μ g * ml-1 (r = 0.999 8), and the average recovery was 97.10% with RSD of 0.63% (n = 6); ConclusionThis method is simple, reliable and reproducible, it can be used for the quantitative determination of the content of Silymarin in Fufang Yiganling tablets. Keywords:: HPLC; Fufang Yiganling tablets; Silymarin Compound Yigan Tablets with Yigan Zishen, detoxification Qushi effect. All side by silymarin, the five-jen alcohol extract composition, clinical for the liver and kidney, lead poisoning caused by damp outstanding Xie Tong, anorexia, abdominal distention, lumbar acid, fatigue, Niaohuang embolism; or chronic hepatitis, transaminase levels were. The main components of drugs for the Compositae Silymarin Milk Thistle Silybum marianum (L.) Gaertn.’s Fruit, refined extract obt