Connexin 43 and Progress in the relationship between disease.docVIP

 PAGE \* MERGEFORMAT 13 Connexin 43 and Progress in the relationship between disease Study: Fan Yingnan Wang Lijun, Li, Xi Huan-long, ZHANG Yue [Abstract] gap junctions is connexin composition of a cell connection. Gap junctions between adjacent cells mediated by gap junctional intercellular communication of information and energy exchange, exchange of materials involved in cell metabolism and electrical coupling signal transduction of electrical coupling of cell metabolism, homeostasis, proliferation and differentiation and other physiological processes important roles. Cx43 is a member of the gap junction protein, and cardiovascular disease, cancer, wound healing and certain reproductive , digestive, nervous system diseases and pathological physiological processes are closely linked. now at home and abroad with a number of diseases, the relationship between Cx43 studies reviewed. [Keywords:] gap junction; Cx43 Abstract: Gap junction (GJ) is a style of cell-cell junction that is constituted by gap junction protein. Through gap junctional intercellular communication mediated by gap junction, flanking cells can exchange message and energy, participate in the metabolism of couple of intercellular substance exchange and couple of electrical signal transmission, which is a role of regulation to metabolism of cells, homeostasis, generation, cell differentiation and so on. Cx43 is a member of the connexin gene family, which is closely linked with cardiovascular diseases, cancer, wound healing, cicatrisation, skin diseases, some reproductive diseases, digestive diseases and nervous system diseases. This paper reviewed some domestic and overseas studies on the relationship between some diseases and Cx43. Keywords:: gap junction; connexin 43 Gap junction (gap junction, GJ) widely exists in mammalian organs, tissues (red blood cells, skeletal muscle excluded), the channel connecting the main components of protein. Currently junction protein found in mam