Continuous blood purification therapy of disseminated intravascular coagulation effect when comparing different anticoagulation.docVIP

 PAGE \* MERGEFORMAT 20 Continuous blood purification therapy of disseminated intravascular coagulation effect when comparing different anticoagulation Of: the right to Liu Tao Xiao Jin-Jun Tian Yang, Zhao Jinsong ZHANG Lin-lin root Qin Yurong Liu Haihua [Abstract] Objective: To study disseminated intravascular coagulation (DIC) were treated with continuous blood purification (CBP) method of treatment of different anticoagulation anticoagulation, and prognostic factors were analyzed. Methods: The emergence of ICU admitted DIC and patients to CBP prospective observational study of 56 cases, a total of 162 cases of second-line treatment of CBP; according to patient mortality 28 d survival group is divided into 21 cases, 35 cases of death; selected according to CBP anticoagulant treatment technologies, into low-dose heparin group, no anticoagulant group, heparin and sodium citrate anticoagulation in vitro in vitro anticoagulation; on prognostic factors and the effects of different anticoagulation. Results : compared with the survival group: CBP treatment, APACHE score higher death group (P lt;0.01), bile duct injury heavier (P lt;0.01), platelet count (BPC) lower (P lt;0.05). different anticoagulation methods between the two groups, CBP after treatment the following morning, patients with low-dose heparin group BPC higher than that before treatment (P lt;0.01), D dimer (D Di) low-dose heparin group than in the non-anticoagulant heparin group and in vitro anticoagulant group (all P lt;0.01); low dose heparin group, the longest single treatment of CBP, and CBP at least complications. Conclusion: DIC patients with effective anticoagulation and close monitoring of coagulation in the premise, can be resistant to by CBP treatment; way in the choice of anticoagulant, low-dose heparin was better. [Keywords:] disseminated intravascular coagulation; continuous blood purification; anticoagulation [Abstract] Objective: To study the effect of different anticoagula