CT and MR evaluation of tumor angiogenesis research.docVIP

 PAGE \* MERGEFORMAT 30 CT and MR evaluation of tumor angiogenesis research Keywords: Tumor Angiogenesis Imaging Review Angiogenesis (angiogenesis) that is the formation of new blood vessels is the body’s growth, development, reproduction and wound healing the essential physiological processes, but also on the local tissue response to ischemia [1]. Tumor angiogenesis in tumor angiogenesis is an existing blood vessel formation process [2]. These new blood vessels can not only promote tumor growth and metastasis, but also caused by blood volume, filling volume and capillary permeability and other changes, therefore, in order to achieve early diagnosis of tumors and accurate evaluation of efficacy, not only requires tumor visual The apparent characteristics of monitoring, but also requires in-depth into the tumor microcirculation and metabolism to explore. With the cell biology, molecular biology and genetics of the rapid development of angiogenesis research has become a unique new areas to explore various aspects of the growth pattern of blood vessels, such as more than 20 kinds of angiogenic factors to promote the identification, sequencing and cloning, the receptor and its signal transduction studies, endogenous angiogenesis inhibitors found in human tumor angiogenesis phenotype characteristics of cytology and molecular biology. In which a variety of imaging imaging methods (CT, MRI, PET, US), in particular, CT, MR functional imaging as a non-invasive, convenient imaging technology, has quantitatively reflect the characteristics of tumor microvessels and tumor angiogenesis-related functions changes, at present experimental and clinical research has become a hot spot, and has an initial clinical application. The new targeted molecular imaging appears to the detection of regulation of vascular growth and proliferation of biochemical factors and means of [3], which is at the molecular level to study the tumor blood vessels opened up new prospects. In