Cytokines in the pathogenesis of bronchial asthma the role of Research.docVIP

 PAGE \* MERGEFORMAT 10 Cytokines in the pathogenesis of bronchial asthma the role of Research [Abstract] bronchial asthma with long-term, cyclical, repetitive significant features, the pathogenesis of asthma are complex, by eosinophils (eosinophils, EOS), mast cells, T lymphocytes and other cells and their secretion of cytokines involved in chronic inflammatory airway diseases, cytokines are the effectors immune cells, the immune regulatory function in the pathogenesis of asthma in the center. [Keywords:] bronchial asthma, cytokines Bronchial asthma (referred to as asthma) are children of the most common chronic respiratory disease, at present, the world has increased the incidence of asthma. British school-age children asthma prevalence of 4% in 1964, 10.2% in 1989, 19.6% in 1994 [1]. the United States 10% to 15% of boys and 7% to 10% of girls had history of asthma attacks [2]. of China in 2000 the prevalence of asthma in urban children in the survey, the incidence of asthma among urban children showed a rising trend [3]. asthma is long-term, cyclical, repetitive significant features, the pathogenesis of asthma are complex, has not yet been clarified, more academics are now being accepted theory is that gas Road chronic inflammation hypothesis. asthma by eosinophils (eosinophils, EOS), mast cells, T lymphocytes and other cells and their secretion of cytokines involved in chronic inflammatory airway diseases, but also a peripheral immune tolerance occurrence of defects by the mechanism of disease [4]. more and more evidence that the activity of cytokines of the immune effector cells, the immune regulatory function in the pathogenesis of asthma in the center. is nearly cytokines in asthma years Pathogenesis reviewed the research progress. 1 IL-3 IL-3 is the eosinophil-activating factor, in patients with allergic allergen stimulation can cause activation of T cells, activated T cells to produce multi-colony stimulating factor, can promote a variet