D galactose SD rat model of sex hormones on the aging the impact of free radical level and the water extract of dogwood nanoparticles Role.docVIP

 PAGE \* MERGEFORMAT 10 D galactose SD rat model of sex hormones on the aging the impact of free radical level and the water extract of dogwood nanoparticles Role Study: Wenyi Cheng Zhang Yu Wang Jiaqi Biande Qiang Liu Lina parsley [Abstract] Objective To investigate the water extract of dogwood and nano-particles of water extract of the aging male SD rats Serum sex hormone levels and superoxide dismutase (SOD activity, malondialdehyde (MDA content. Methods D galactose injecting intraperitoneally subacute aging model, fed by stomach 0.57 g kg-1 d-1 of the water extracts and the dogwood Cornus nanoparticles water extracts 30 d, using xanthine oxidation in serum SOD activity, sulfur on behalf of the barbituric acid (TBA assay of serum MDA, sex hormone levels was detected by electrochemiluminescence. Results D galactose androgen levels in rats, SOD activity was significantly lower than normal group (P lt;0.01), MDA content increased significantly (P lt;0.01), while the water extract of dogwood, and Cornus nanoparticles can effectively improve the water extract of serum SOD activity in aging model (P lt;0.05, P lt;0.01), male hormone levels (P lt;0.01), decreased aging MDA content in rats, compared with the model group were significantly different (P lt;0.01). and the water extract of nanoparticles superior efficacy of water extract of dogwood (P lt;0.05). Conclusion dogwood subacute aging by improving large mouse serum testosterone levels, improve antioxidant capacity, inhibition of lipid peroxidation play a role in delaying aging, and the nanoparticles more effective than water extracts water extract dogwood. [Keywords:] dogwood; aging; hormone; nano-particles Human aging and gonadal structure and function is closely related to the degradation, the kidney and the research often found in anti-aging medicine reported. The current study shows that treatment with the hormone to prevent aging and menopause syndrome is beneficial, but there are many def