Decoction on rat lung and thymus expression of nerve growth factor.docVIP

 PAGE \* MERGEFORMAT 11 Decoction on rat lung and thymus expression of nerve growth factor Of: Li Jie, Wu Rong participation, Chen Ling-Li, Li Jihong, Jiang Xiao, Yang Chen North [Abstract] Objective Decoction on rat lung and thymus of nerve growth factor (NGF) in rats. Methods 32 Wistar rats were randomly divided into normal control group, model group, Dingchuantang group, will be ketone group, n = 8. In addition to the normal control group, asthma model prepared by the other groups, and each medication, a total of 15 d. immunohistochemical methods, lung and thymus of rats the expression of NGF. Results of model group big mouse NGF in the lungs and thymus was significantly higher than the normal control group, while the DCT group was significantly lower than the untreated group. Conclusion NGF may be involved in the pathogenesis of asthma, Ding Chuan Tang in asthmatic rats may be the expression of NGF treatment one of the mechanisms of asthma. [Keywords:] Dingchuantang, nerve growth factor, lung, thymus, asthma, rat Effect of Dingchuantang on Expression of NGF in Lung and Thymus of Asthmatic Rats LI Jie, WU Can-rong, CHEN Ling-li, et al Hunan University of TCM, Changsha 410007, China Abstract: Objective To explore the effect of Dingchuantang on the expression of NGF in the lung and thymus of asthmatic rats. Methods Thirty two Wistar rats were randomly divided into control group, asthmatic group, Dingchuantang group and Beclomethasone group, 8 rats for each group. Asthmatic model was made except the control group. The change of NGF expression in the lung and thymus were observed by means of immunohistochemistry. Results The expression of NGF in the lung and thymus of asthmatic group was much higher than that of control group and that of Dingchuantang group was much lower than that of asthmatic group. Conclusion Over-expression of NGF might be involved in the pathogenesis of bronchial asthma, and inhibition of NGF expression by Dingchuantang