Deficiency on the spleen and kidney of the rat brain somatostatin receptor gene expression levels and the impact of.docVIP

 PAGE \* MERGEFORMAT 11 Deficiency on the spleen and kidney of the rat brain somatostatin receptor gene expression levels and the impact of Study: Money will be the South, Wang Yue, Hu Xueqin Shen Libo [Abstract] Objective To compare the spleen and kidney deficiency model of rat brain somatostatin (SS) levels and receptor gene expression. Methods down purgative bitter, tired of over-eating disloyal hard labor was established by spleen deficiency rats to immunohistochemistry and in situ hybridization ventral hypothalamic nucleus, hippocampus CA1 area, the prefrontal cortex of SS and somatostatin receptor 1 (SSR1) mRNA gene expression. Results of model group the SS immunoreactivity in brain regions material and SSR1 mRNA expression was significantly lower positive reaction, with significant difference between the normal group, kidney and spleen group and SS group, these brain regions and the positive immunoreactive positive reaction SSR1 mRNA expression increased significantly compared with model group differences significant compared with the normal group no significant difference. Conclusion deficiency on learning and memory in rat brain cortex can promote the SS level and SSR1 mRNA gene expression changes in spleen and kidney and may regulate gene expression in SS level and SSR1 affect learning and memory. Keywords:] deficiency model, somatostatin, somatostatin receptor 1 mRNA expression, rat Abstract: Objective To compare on the influence of invigorating spleen and restoring virility to the SS level and SSR1 gene expression in brain. Method The spleen insufficiency model of rat was established by adopting bitter decline diarrhea, wild eating and overworking. SS level and SSR1 gene expression change of hypothalamus ventral kernel, hippocampi CA1 area and forehead corte were detected by immunohistochemistry and in situ hybridization techniques. Result In the model group, the immunoreaction masculine substance of SS and SSR1 mRNA, hypothalamus ven