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Diabetes mellitus and the relationship between colorectal cancer and metastasis
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Diabetes mellitus and the relationship between colorectal cancer and metastasis
[Abstract] [Objective] To understand diabetes and colorectal cancer and its metastasis. [Methods] Case-control method of analysis in our hospital 364 cases of colorectal cancer patients and 733 cases of non-cancer patients with diabetes mellitus. [Results] diabetic patients suffering from colorectal cancer risk 1.72 times that of non-diabetic patients; a history of diabetes in patients with colorectal cancer risk transfer took place is no history of diabetes, 1.94 times; Multivariate Logistic regression analysis showed that: the history of diabetes, of colorectal cancer independent risk factor for illness. [Conclusion] Diabetes increases the risk of colorectal cancer risk, and also accelerate the transfer of colorectal carcinoma.
[Keywords:] Colorectal cancer
Colorectal cancer (colorectal cancer, CRC) in recent years, the incidence increased year by year, seriously endangering people’s health. According to sample survey of cancer mortality and prediction in 2005, colorectal cancer mortality, significant increase compared with 2000, men ranked five, women ranked 6 [1]. Previous studies have shown that colorectal cancer and genetic factors, dietary fat, meat, and physical activity so close. In recent years, epidemiological studies found that prevalence of colorectal cancer with diabetes (diabetes mellitus, DM) close to [2 ~ 4]. Currently on the relationship between diabetes and colorectal cancer research little. To further clarify the diabetes and the relationship between the prevalence of colorectal cancer, this study used case-control approach, research and analysis of colorectal cancer patients with diabetes-related reasons, to explore the etiology of colorectal cancer as well as the provision of primary prevention of colorectal cancer ideas.
1 Materials and methods
1.1 Materials
Cases from September 2003 to December 2005 at Xuanwu Hospital, Capital Med
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