Different Chinese herbal compound on the avian influenza virus infection in mice.docVIP

 PAGE \* MERGEFORMAT 15 Different Chinese herbal compound on the avian influenza virus infection in mice Of: Liu Zhonghua, Zhang Wei, Lin Peizheng, Huang Ren, Hai Zou shift [Abstract] [Objective] To observe the traditional Chinese medicine on the avian influenza virus infection in mice. [Method] BALB / c mice were divided into groups Huo Xiang Zheng Qi San (Agastache rugosa group, a dose of 26 4 g kg-1 d-1), Gui Zhi Tang group (dose of 15 6 g kg-1 d-1), Sang Ju Yin groups (dose of 34 4 g kg-1 d-1 ), ribavirin group (dose of 70 mg kg-1 d-1), model group, control group allantoic fluid (allantoic fluid group). according to the design of each group after dose 3 times to 100 L normal allantoic allantoic fluid droplets into the nasal cavity of mice and other mice in each group to 100 L H5N1 avian influenza virus intranasally, replication of avian influenza mouse model. general of mice, body temperature, body weight, death protection rate and lung index. [Results] The body temperature of mice was significantly decreased (P lt;0 05), 3 groups were Chinese herbal compound on the body temperature of mice has a protective effect (P lt;0 05), followed by the role of strength Patchouli righteousness for the bulkgt; Gui Zhi Tanggt; Sang Ju Yin. model group were significantly decreased body weight (P lt;0 05), 3 groups of mice traditional Chinese medicine can reduce the body weight decreased (P lt;0 05) , the role of the strength of the order of Sang Ju Yingt; Gui Zhi Tanggt; Huo Xiang Zheng Qi San .3 can extend the model of traditional Chinese medicine group survival time of mice, followed by death protective effect of the strength of Gui Zhi Tanggt; Huo Xiang Zheng Qi Sangt; Mulberry Ju drink. model was significantly higher in lung (P lt;0 05), 3 groups of Chinese medicine compound can significantly reduce the lung index (P lt;0 05), and 3, inhibition of lung indices were higher than ribavirin group. [Conclusion] Huo Xiang Zheng Qi San, Gui Zhi Tang,