Differentiation of bone marrow mesenchymal stem cells to regenerate sweat glands and blood vessels dominated the organization of neural.docVIP

 PAGE \* MERGEFORMAT 18 Differentiation of bone marrow mesenchymal stem cells to regenerate sweat glands and blood vessels dominated the organization of neural Of: Fu Xiaobing, Sun with the column, Lei Yonghong, including Xiaoxia, Cui-Ping Zhang, Zhi-Yong Sheng [Abstract] Objective To study the differentiation of bone marrow mesenchymal stem cells to regenerate sweat glands Organization of the nerve and blood vessel distribution in order to confirm the regeneration of sweat glands organization by the new Nerves and angiogenesis of the blood supply, in order to evaluate regeneration of sweat gland tissue quality. Methods underwent excision of burn scar 4 patients. Prizes will be awarded for each patient the wound with autologous bone marrow mesenchymal stem cells (MSCs) transplantation and the control of two parts. grafted sites in the vaccination scar on the wound after excision-induced MSCs, while the control site in addition MSCs are not vaccinated, the other way with the treatment of wounds. after 3 months in the grafted sites and control sites respectively sweat test. In the sweat test was positive for the injected sites, drawn at the same time taking control of parts of the organization and operation scar cut organization. using two-step immunohistochemical detection of tissue samples taken from the S 100 protein (S 100), neuron-specific enolase (NSE), VIII factor related antigen ( R Ag) and CD34 expression, and with compared with normal skin. Results wounds grafted sites 4 cases were positive sweat test, sweat test negative control site. immunohistochemistry showed parts of the dermal graft has a structure similar to the shallow tissue mass normal sweat glands, but not the control site observed similar structures. S 100, NSE, R Ag and CD34 in the graft site and control site, scar tissue and normal skin were expressed, and S 100, NSE, R Ag and CD34 sweat glands in the transplanted tissue regeneration in the area distribution of sweat glands in norm