Dogs with acute left ventricular ischemia and reperfusion model of myocardial function by strain rate imaging and reactive oxygen species levels.docVIP

 PAGE \* MERGEFORMAT 10 Dogs with acute left ventricular ischemia and reperfusion model of myocardial function by strain rate imaging and reactive oxygen species levels Of: Cao Zhenjiang Dong Fan Shen Song Yang Di High [Abstract] Objective strain rate imaging (SRI) technique to observe dogs with acute myocardial ischemia and reperfusion of regional myocardial systolic function was also measured levels of reactive oxygen species. Methods 30 healthy dogs were randomly divided into control group, ischemic group and reperfusion group. SRI model of the three groups measured by peak systolic myocardial strain (SSYS) and peak strain rate (SRSYS), flow cytometry of myocardial cells and peripheral blood reactive oxygen species (ROS) levels. Results Ischemia of the left anterior chamber and the middle section before the interval and SRSYS SSYS significantly lower, compared with the control group had significant difference (P lt;0.01), reperfusion of left ventricular anterior wall and interventricular septum and the middle section of SSYS SRSYS comparison with ischemic group has l high, but still lower than the control group (P lt;0.01). myocardial cells and mean fluorescence intensity of ROS in peripheral blood, ischemia group was higher (P lt;0.05), significantly higher than reperfusion group and ischemia group (P lt;0.01), three groups had significant difference. Conclusion SRI technology can accurately determine regional myocardial ischemia and reperfusion contractile function, myocardial ischemia and reperfusion injury during the ROS increase. [Keywords:] strain rate imaging; ischemia-reperfusion; myocardial function; reactive oxygen species Strain rate imaging (strain rate imaging, SRI) technology is based on tissue velocity imaging in the development of a new technology (1), theoretically pull effect from the adjacent myocardium and cardiac translation of the whole, better than the speed parameters reflect the intrinsic biomechanical properties of the m