Dou Chu Fang on Ehrlich ascites carcinoma ascites in mice in vivo study of.docVIP

 PAGE \* MERGEFORMAT 17 Dou Chu Fang on Ehrlich ascites carcinoma ascites in mice in vivo study of Author: Peng Haiyan, Zhang Yonghong, Yang morning, Ye Lihong, Zhang Xiaochun, Ren Fengmei Keywords: soybean Chu Fang;,, Ehrlich ascites carcinoma;,, mouse;,, life span Abstract: Objective To observe the beans Chu Fang on Ehrlich ascites carcinoma (EAC) ascites-type mice in vivo. Methods 50 Kunming mice were randomly divided into 5 groups: In the model the negative control group (A), 5Fu positive control group (B), beans Chu Fang high-dose group (C), beans Chu Fang-dose group (D), beans Chu Fang low dose group (E). EAC mice inoculated 8 d after the continuous intragastric administration, a time / d, observed and recorded animal body weight, general conditions and time of death. Results Compared with model group, beans, and Chu Fang tumor-bearing mice with various doses of the general situation is better and significantly prolonged survival time. Conclusion beans Chu, has the role of anti-EAC ascites. Keywords:: beans Chu Fang; Ehrlich ascites carcinoma; mouse; life span Bean Chu party is the 20th century, a famous traditional Chinese medicine, Jiangsu 70s material experience of liver specialists Liang-Fang, has been used for “Yin bulging” certificate of treatment, our clinical observation to this side of ascites due to cirrhosis [1], liver, ascites [2] has significant therapeutic effect, using Ehrlich ascites carcinoma (EAC) ascites mouse model to carry out this side of the mouse ascites tumor growth and survival in rats. Are reported below. 1 Materials 1.1 Animals Kunming mice were 50 healthy adult, both male, average weight (19.2 ± 1.49) g, from Nanjing University of Traditional Chinese Medicine Experimental Animal Center. 1.2 tumor strains of EAC tumor lines by the Jiangsu Provincial Tumor Hospital Center for Experimental Pharmacology, 7 ~ 10 d passaged one time, in the abdominal cavity after passing three