Drug treatment of bronchial asthma Progress.docVIP

 PAGE \* MERGEFORMAT 15 Drug treatment of bronchial asthma Progress [Abstract] treatment of asthma drugs in recent years, reviewed the application. On the treatment of bronchial asthma in the clinical application of drug analysis. A new clinical use of anti-asthma drugs with good efficacy, less side features. With the deepening of the pathogenesis of asthma , the continuous development of new drugs, asthma treatment has made great progress, showing good prospects. [Keywords:] Asthma; treatment; progress Bronchial asthma is a common respiratory disease, the last 10 years many countries have an upward trend in the prevalence of [1], is a serious threat to public health one of the major chronic diseases. Therefore it is important to treat asthma, clinical asthma article drugs are summarized below. Anti-asthma medication is currently divided into three categories and other categories: the elimination of non-specific inflammatory drugs, inhibition of allergic mediator release drugs, agents and other types of bronchial dilation [2]. 1 to eliminate non-specific inflammatory drugs Glucocorticoids are the most effective non-specific inflammation of the airway to eliminate drugs, is still the most effective anti-inflammatory drugs, mechanism of action is to: prevent the inflammatory cells especially eosinophil chemotaxis and activation; inhibition of cytokine generation; interference carbon metabolism of arachidonic acid; inhibition of leukotriene and prostaglandin synthesis and release of inflammatory mediators; reduce microvascular leakage; increased 2 agonist on tracheal smooth muscle responsiveness [2-3]. The route of administration, including inhalation, oral and intravenous. Glucocorticoid adverse reactions, it is mainly used for systemic treatment of acute or severe asthma attack. inhaled corticosteroids are the treatment of chronic persistent asthma drug of choice. Many studies have confirmed that they improve lung function, reduce