Drug treatment of malaria.docVIP

 PAGE \* MERGEFORMAT 12 Drug treatment of malaria [Abstract] malaria (malaria) is the human malaria parasite transmitted by the Anopheles vector endemic infectious diseases. Clinical features of a chronic chills, fever, sweating and fever. Popular in southern China. [Keywords:] Western medicine treatment of malaria endemic infectious diseases First, the etiology Pathogens to human malaria parasites. Is divided into four types: Plasmodium vivax (Plasmodium vivax), P. falciparum (P.falciparum), Plasmodium three days (P.malariae) and Plasmodium (P.ovale). The life cycle consists of two phases, namely, the proliferation of the human body for the asexual stage and the sexual in vivo proliferation of Anopheles stage. Anopheles with Plasmodium sporozoite salivary fluid into the blood, with blood invasion of liver cells to begin nuclear fission, the splitting proliferator and emit a large number of merozoites. vivax sporozoite development were two forms: hair sporozoite rate, delayed sporozoite. merozoites invade red blood cells, the ring body, large trophozoites, schizont stages of development, the formation of merozoites, with the release of red blood cells rupture, which can then invade other red blood cells continue to asexual proliferation. generations of development for the latter part of the gametophyte, the Anopheles inhalation, in mosquitoes by the gamete, zygote, ookinete, capsule, etc. zygote formation of sporangium maturation stage, capsule containing many sporozoites, sporozoites enter the Anopheles salivary gland capsule breaking, blood-sucking again when injected into the human body. Second, the clinical manifestations (A) Typical attack Average incubation period of 14d. In three phases. 1. Cold chills of a sudden, severe shivering, lips cyanosis, pulse fine speed, the end of the body temperature gradually rose. Continued a few minutes to 1h. 2. Fever of chills stop, followed by high fever, body temperature