Dragon#39;s Blood extract on normal and alloxan diabetic model mice.docVIP

 PAGE \* MERGEFORMAT 8 Dragon#39;s Blood extract on normal and alloxan diabetic model mice Author: Liu Peipei, Yong Ke Lan, Jing-Ci Lü, Luan-mei, ZHANG Tian-bao Keywords: Dragon’s Blood extract;,, alloxan;,, glucose;,, insulin;,, serum Abstract: Objective To study the Dragon’s Blood extract on normal and alloxan diabetic model mice. Methods normal mice and alloxan-diabetic mice, using glucose oxidase determination of glucose, measured by radioimmunoassay of serum insulin, high-performance liquid chromatography (HPLC) analysis of mouse serum. Dragon’s Blood extract the result of normal mice significantly reduced the role of fasting blood glucose can reduce the alloxan diabetic mice, fasting blood glucose levels, can improve the tolerance of mice to sucrose and increase insulin secretion in normal mice, Serum samples had detectable drug ingredients. Conclusion Dragon’s Blood extract on diabetic mice have a better therapeutic effect could increase serum insulin levels, some of its components can be absorbed and enter the blood in animals play a role. Keywords: Dragon’s Blood extract; Alloxan; blood glucose; insulin; serum Glucosedecreasing Effect of Extract from Resina Draconis on Mice Abstract: ObjectiveTo study the effect of extract from on mice. MethodsNormal mice and alloxaninduced diabetic mice were used. Blood glucose was measured with glucose oxidase method, and insulin was measured with radioimmunoassay, and the serum in mice was analyzed by HPLC. ResultsResina Draconis had no obvious effects of decreasing the serum glucose level in normal mice, but could decrease the serum glucose level in alloxaninduced diabetic mice. Also, Resina Draconis improved the sucroseresistance in normal mice and diabetic mice and increased insulin in normal mice. Some of components of Resina Draconis had been measured in serum sample. ConclusionResina Draconis exerts have a good therapeutic effect on alloxaninduced diabetic mice and its mechani