Drug treatment of hypertension Progress.docVIP

 PAGE \* MERGEFORMAT 25 Drug treatment of hypertension Progress [Keywords:] anti-hypertensive drugs; cardiovascular; ideal target blood pressure levels Although the treatment of hypertension has been tremendous progress, but the control rate is still not ideal, single-drug therapy have certain limitations, combination therapy received extensive attention in recent years, and as jnc  vi and who / ish guide antihypertensive drug therapy, one of the important principles , high blood pressure diagnosis and treatment of the concept has been updated, hypertension is not only the hemodynamic disorders, but also accompanied by fat, sugar metabolism disorders and heart, brain, kidney and other target organs, adverse remodeling. Therefore, effective control of blood pressure treatment to the level of the same time, improve the various metabolic disorders, prevent and reverse the negative remodeling in target organs, which is to reduce the incidence and mortality of cardiovascular complications in the key. This paper made in order to review the drug treatment of hypertension as well as new progress is introduced. In recent years, with a large-scale clinical trials to carry out anti-hypertension and cardiovascular molecular biology progress of the study, the conventional understanding of high blood pressure has been updated, evidence-based medicine has become a consensus. Hypertension is not only the hemodynamic disorders, but also accompanied by fat, sugar metabolism disorders and heart, brain, kidney and other target organs, adverse remodeling. Therefore, effective control of blood pressure treatment to the level of the same time, improve the various metabolic disorders, prevent and reverse the negative remodeling in target organs, which is to reduce the incidence and mortality of cardiovascular complications in the key. A hypertensive blood pressure goal of Step-down objectives, namely the ideal blood pressure levels, blood pressure sh