Elderly patients after surgery on cognitive impairment in research.docVIP

 PAGE \* MERGEFORMAT 15 Elderly patients after surgery on cognitive impairment in research Of: the right to Shonkin Miao Xie Jun Xie Tao Hong [Keywords:] cognitive function, the elderly, barriers Often appear in elderly patients after surgery neuropsychiatric complications, the performance of mental disorder, anxiety, personality changes and impaired memory. The post-operative personality, social skills and changes in cognitive abilities and skills as cognitive function after surgery disorder (POCD) (1). Most of the incidence of POCD and its mortality. In particular, preoperative anxiety and postoperative personality changes, memory impairment, etc. can lead to increased postoperative mortality. POCD mainly for surgery decline in memory and attention after the degradation of brain function, characterized by the general anesthesia induced and do not belong to delirium, dementia, forgetting the clinical types of obstacles. POCD occurred more common in elderly patients, many safety through the anesthesia and surgical patients complained of post-operative 1 w ~ 3 months, have a certain psychological barrier. for some post-operative patients, short (a few weeks to several months of cognitive impairment will only bring some trouble, but the damage will be lasting enable the elderly to lose some of the life and work skills. 1 POCD incidence and mechanisms 1.1 The incidence of POCD mainly occur in the heart and other major surgery. It has been reported more than 60 years old after 1 w ~ 3 months, the persistence of cognitive dysfunction, and even last a year or years (2). Another studies suggest that (3) only occurs in elderly patients with POCD after 1 day. 1.2 POCD may be associated with the elderly brain acetylcholine (Ach) content of cholinergic presynaptic nerve degradation and reduce the number of acetylcholine receptors in the brain related to a number of areas, hypothalamus and caudate nucleus dopamine content decreased catecholaminergic , cho